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KMID : 0360319940260040561
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Journal of Korean Cancer Research Association
1994 Volume.26 No. 4 p.561 ~ p.566
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Concurrent Chemoradiotherapy of Locally Advanced Pancreatic Carcinoma and Effects of Hyperthemia
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김명욱
이경희/정재복/성진실/이혜란/최진혁/정현철/김우철/금기창
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Abstract
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The prognosis of pancreati cancer is still poor in spite of advance in surgical treatment and parasurgical adjuvant management.
Eighteen patients with histologically confirmed locally advanced adenocarcinoma of the pancreas were received radiation(5000cGy)+5-FU. Patients were treated with 5-FU 200mg/㎡ IV bolus, 1 hour before irradiation each day. In some patients, within
30
minutes after radiotherapy, hyperthemia was added to above protocol two times weekly. Median survival of total patients was 9.5months. Median survival with RT+5-FU was 12.7 months from the date of treatment. Median survival with hyperthemia added
group
was 7.6months, but the survival difference was not significant statistically. The side effects were acceptable. There were no episodes of any life threatening toxicities.
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KEYWORD
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